The authors investigated breakthrough SARS-CoV-2 infections in health care workers by performing extensive evaluations of those who were symptomatic or had known infection exposure. Source: AAO
A review of cases from a single practice in the United States was conducted to determine the incidence of divergence insufficiency (DI) esotropia over a 41-year period. Source: AAO
COLUMBUS-AMD is a multicenter, parallel-group, 48-week phase III clinical trial that assessed the equivalence of FYB201, a candidate biosimilar for ranibizumab, with reference ranibizumab. Source: AAO
Investigators compared telemedicine utilization among pediatric ophthalmologists in the United States at the beginning of the COVID-19 pandemic and several months into the pandemic. Source: AAO
A recent retrospective study assessed whether the use of topical ocular antihypertensives affected outcomes of dacryocystorhinostomy (DCR) with intubation. Source: AAO
Retrospective data from patients enrolled in a large US healthcare system were used to evaluate rates of complicated acute posterior vitreous detachment (PVD). Source: AAO
Investigators in Italy used a nonrandomized prospective comparative case series to compare visual outcomes with monofocal, enhanced monofocal, and extended depth-of-focus (EDOF) IOLs. Source: AAO
A group of stapled peptides was designed to disrupt viral DNA synthesis by mimicking a structure of the herpes simplex virus-1 (HSV-1) polymerase. African green monkey kidney epithelial cells were cultured and treated with unstapled and stapled peptides, and blocking of HSV-1 DNA synthesis and infection were assessed. Source: AAO
A retrospective, population-based review conducted over 50 years in a single county in the United States evaluated the risk of developing diabetes-associated ocular complications (DAOC) in children diagnosed with either type 1 or type 2 diabetes. Source: AAO
The phase II MYSTIC clinical trial for the small-molecule nicotinic acetylcholine receptor agonist varenicline nasal spray (VNS), showed rapid onset of tear production and immediate relief reported by patients with dry eye disease. Source: AAO
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