A phase 1 study found that a novel intravitreal gene therapy that induces aflibercept production may be able to minimize reliance on anti-VEGF injections in patients with neovascular AMD. Source: AAO
Intracameral (IC) phenylephrine is often used to prevent intraoperative floppy-iris syndrome (IFIS) and initiate mydriasis during cataract surgery, but as the drug is known to have cardiovascular effects proper dosing is important. Source: AAO
In eyes that need cataract surgery and have had previous myopic laser surgery vision correction (M-LVC), newer IOL power calculation formulas with posterior keratometry values may provide more accurate information than older formulas. Source: AAO
Children with congenital cataract and their parents seem comfortable with eye patches, glaucoma medication adherence may be affected by sociodemographic factors, dementia prediction could be improved by adding visual perception screening, and more. Source: AAO
In a patient with an extensive choroidal tumor, the use of oral darovasertib and crizotinib reduced the mass to a size suitable for plaque radiation therapy, preserving the eye and the patient’s vision. Source: AAO
Certain demographic and physical indicators, such as age and body mass index (BMI), can have an influence on myopia development in adolescents. Source: AAO
A retrospective, population-based cohort study found that during a 10-year period, female comprehensive cataract surgeons in Ontario, Canada, had less allocated time in the operating room (OR) than their male counterparts, despite having a similar caseload. Source: AAO
A case series investigation of 7 patients with mosaic RASopathy identified novel clinical features that could help differentiate disease-associated ocular masses from typical choroidal osteomas. Source: AAO
Changes in corneal astigmatism were found to be pronounced in some patients who had surgery for blepharoptosis, particularly those with more severe disease. Source: AAO
An autonomous artificial intelligence model showed good ability to detect patients with moderate or worse retinopathy of prematurity (ROP) when tested among 2 large, multinational datasets. Source: AAO