A retrospective, population-based review conducted over 50 years in a single county in the United States evaluated the risk of developing diabetes-associated ocular complications (DAOC) in children diagnosed with either type 1 or type 2 diabetes. Source: AAO
The phase II MYSTIC clinical trial for the small-molecule nicotinic acetylcholine receptor agonist varenicline nasal spray (VNS), showed rapid onset of tear production and immediate relief reported by patients with dry eye disease. Source: AAO
The American Academy of Ophthalmology has published its recommendations against routine screening of patients for endophthalmitis caused by Candida septicemia. Source: AAO
Investigators in Sweden conducted a prospective cohort study to evaluate recurrence of active macular revascularization and visual outcomes in patients who previously underwent anti-VEGF treatment for neovascular AMD. Source: AAO
This week, global retinoblastoma survival disparities remain despite progress. the first generic for Restasis is approved in the US, and ophthalmic problems due to prematurity persist into adulthood. Source: AAO
Investigators conducted a retrospective analysis of Medicare claims data to evaluate the economic and reintervention burdens of incisional glaucoma surgery failures. Source: AAO
The authors investigated the association of simulated COVID-19 vaccine efficacy and nonpharmaceutical interventions (NPIs) (reduced mobility, school closings, and use of face masks) with rates of infection, hospitalization, and death. Source: AAO
The authors investigated the presence of presumed SARS-CoV-2 viral particles in the eyes of patients who had died of COVID-19 and found evidence of the virus in multiple layers of the retina and choroid. Source: AAO
End-of-study results for the extension phase of the phase 2 Ladder trial, comparing use of the Port Delivery System (PDS) and monthly intravitreal injections of ranibizumab for neovascular AMD, suggest comparable efficacy outcomes. Source: AAO